Public Recipes
Materials and Chemicals:
For Synthesis of Piperidine:
Acetone (500 mL)
Ammonium chloride (50 g)
Calcium hydroxide (50 g)
Distillation setup (all including round-bottom flask, condenser, receiving flask)
pH meter or pH paper, prefferably the meter since you dont have to keep dipping the paper in the solution
Heating mantle or hot plate/stirrer, dont use gas just use an electric one its so much easier
Glassware for measurements (beakers, graduated cylinders)
Glass stirring rods
Synthesis of Piperidine:
-Preparation of Ammonium Chloride Solution:
-Dissolve 50 g of ammonium chloride in 300 mL of water in a round-bottom flask.
-Add 50 g of calcium hydroxide to the solution and stir until dissolved.
-Set up a distillation apparatus with the round-bottom flask containing the solution as the boiling flask, ensuring proper attachment of the condenser and receiving flask.
-Heat the solution to reflux for 4 hours at 100°C (212°F).
-Collection of Piperidine:
-Collect the distillate in the receiving flask.
-Piperidine will distill over and be collected. It usually comes over around 106-108°C (223-226°F).
-Monitor the pH of the solution and ensure it remains alkaline (pH around 11-12). Add more calcium hydroxide if necessary.
-Once the distillation is complete, allow the collected piperidine to cool to room temperature, you might wanna check the purity though. More coming soon!